论文部分内容阅读
将一例肾切除.另侧肾夹闭肾动、静脉和输尿管2小时造成急性缺血性肾功能衰竭的18只家兔随机平分三组。第Ⅰ组不加治疗,用作对照;第Ⅱ组用低分子右旋糖酐作等容量血液稀释;第Ⅲ组用GBK 液作二倍容量血液稀释。三组动物在同等条件下饲养,观察、比较其血尿素氮含量,无尿时间,尿量变化,存活时间和死后肾组织学改变。结果显示血液稀释有降低急性缺血性肾功能衰竭动物血中尿素氮,缩短动物无尿时间,提高动物存活率和减轻肾缺血造成的肾损害等作用。
Eighteen rabbits with acute ischemic renal failure were sacrificed and equally divided into three groups. One nephrectomy was performed. The other kidney was clamped to the renal artery, vein, and ureter for 2 hours. Group I received no treatment, and was used as a control; Group II was treated with low-molecular-weight dextran for equal volume hemodilution; Group III was treated with GBK fluid for double-volume hemodilution. The three groups of animals were reared under the same conditions, and the blood urea nitrogen content, anuria-free time, change in urine volume, survival time, and histological changes after death were observed and compared. The results showed that hemodilution had the effects of reducing blood urea nitrogen in animals with acute ischemic renal failure, shortening animal anuria time, improving animal survival and reducing kidney damage caused by renal ischemia.