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抗体对麻风病人并不具有保护作用。由于抗体是抗原刺激后的早期表现,因此抗体测定可作为早期诊断亚临床感染的工具,并且可作为治疗中的观察指标。过去用全麻风菌或部份纯化的麻风菌提取物作抗原与先经其它分枝杆菌吸收过的、消除了交叉反应抗体的血清进行测试。近来发现从感染麻风菌的犰狳组织可以提取大量麻风菌特异性酚糖脂(PhenolicGlycolipid,PGL-1),从而开创了麻风血清学新的远景。至于用全麻风菌或其它分枝杆菌为抗原与未加预先吸收的血清起反应的
Antibodies do not have a protective effect on leprosy. Because antibodies are an early manifestation of antigen stimulation, antibody assays can be used as a tool for early diagnosis of subclinical infections and can be used as an indicator of treatment. In the past, alloplasmic or partially purified leprosy extracts were used as antigens to be tested against sera previously abstracted by other mycobacteria and abrogated by cross-reacting antibodies. It has recently been found that a large amount of Phenolic Glycolipid (PGL-1) can be extracted from the tissue of the arm of Leprosy infected with Leprosy to create a new prospect of leprosy. As for the use of Anemonecis or other mycobacteria as antigens with no pre-absorption of serum reaction