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目的 研究接触低浓度二异氰酸甲苯酯 (TDI)对工人健康的影响。方法 通过健康体检对 34例接触组工人与 32名对照组工人进行比较研究。结果 接触组工人头昏、手足多汗、乏力、咽痛、皮疹等症状发生率高于对照组 (P<0 0 5 ) ,接触组工人FVC、FEV1、FEV1/FVC、HR(心率 )及全血胆碱酯酶活性均低于对照组 (P <0 0 1) ,而接触组的RMSSD则高于对照组 (P <0 0 1)。结论 低浓度的TDI对工人的呼吸道功能、胆碱酯酶的活性和RMSSD均有一定的影响
Objective To investigate the effects of exposure to low concentrations of tolylene diisocyanate (TDI) on workers’ health. Methods Through the physical examination, 34 workers in the contact group and 32 workers in the control group were compared. Results The incidence rate of dizziness, hand sweat, sweating, fatigue, sore throat and skin rashes in the exposed group were higher than those in the control group (P <0 05), FVC, FEV 1, FEV 1 / FVC, HR Blood cholinesterase activity was lower than the control group (P <0.01), while the contact group RMSSD was higher than the control group (P <0.01). Conclusions Low concentrations of TDI have some effects on respiratory function, cholinesterase activity and RMSSD in workers