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对５３例斜视病人进行眼外肌注射Ａ型肉毒杆菌毒素治疗。注射后近期最大斜视矫正度平均为４０．５８△（０～１１０△），中度疗效与显效占８４．９１％。对其中４３例进行６～３６个月（平均１４．４个月）远期疗效的观察，平均矫正斜视度１９．６５△。２１例病人行重复注射。有１１例病人最终获得了正常的双眼单视维持１８～２２个月。讨论了Ａ型肉毒杆菌毒素治疗斜视的适应证、远期疗效和重复注射的指征。
Fifty-three patients with strabismus received extraocular muscle injection of botulinum toxin type A. The maximal correction of maximal strabismus in the near future was 40.58 △ (0 ~ 110 △) after injection. The moderate and significant effects were 84.91%. The long-term curative effect was observed in 43 cases of 6 to 36 months (average 14.4 months), with an average corrected strabismus of 19.65 △. 21 patients repeated injections. Eleven patients eventually achieved normal binocular vision for 18 to 22 months. The indications for the treatment of strabismus with botulinum toxin type A, long-term efficacy, and indications for repeated injections were discussed.