国内外由多种病原微生物所致的感染性疾病发病率和病死率很高,其中细菌性感染最为常见,因此抗菌药物已成为临床应用最广泛的药物之一。抗菌药物在治愈并挽救了许多感染性疾病患者生命的同时,也出现了由于抗菌药物不合理应用而导致了不良后果,如不良反应的增多、细菌耐药性的增 At home and abroad by a variety of pathogenic microorganisms caused by infectious diseases, high morbidity and mortality, of which bacterial infections are the most common, so antibacterial drugs have become one of the most widely used drugs. Antimicrobial drugs in the cure and save the lives of many patients with infectious diseases, but also due to the irrational use of antimicrobial agents led to adverse consequences, such as increased adverse reactions, increased bacterial resistance