基因表达是预测癌症预后的重要依据。目前对多数单基因在相关临床表型中所起的作用尚不清楚。αB-晶体蛋白是热休克蛋白(HSP)家族中的成员,主要在神经胶质细胞瘤、前列腺肿瘤和肾细胞肿瘤中表达。Moyano等发现αB-晶体蛋白在基底样乳腺肿瘤中也可能有潜在致癌作用,因为乳房肿瘤 Gene expression is an important basis for predicting the prognosis of cancer. The role of most single genes in the relevant clinical phenotype is unclear at present. Alpha B-crystallin is a member of the heat shock protein (HSP) family and is expressed primarily in glioma, prostate and renal cell tumors. Moyano et al. Found that αB-crystallin may also have a potential carcinogenic effect in basal-like breast tumors because breast tumors