为了寻找天然的新型速激肽NK_1受体阻滞剂,检测了约200种植物提取物的速激肽阻滞活性,从菊科植物提取物中获得了1个有效的速激肽NK_1受体阻滞剂。 菊科植物母菊(Matricaria chamomilla)的干燥花头(400g)在室温下用甲醇提取,过滤,甲醇提取液挥干,得到残余物(78.8g)。取少量残余物(20mg)经ODS柱色谱分离,获得的各部分干燥, In order to find the natural novel tachykinin NK_1 receptor blocker, about 200 plant extracts were tested for tachykinin blockade activity, and an effective tachykinin NK_1 receptor was obtained from the extract of Compositae. Blocker. The dried flower head (400 g) of Compositae Matricaria chamomilla was extracted with methanol at room temperature, filtered, and the methanol extract was evaporated to give a residue (78.8 g). A small amount of residue (20 mg) was separated by ODS column chromatography and the obtained fractions were dried.