由Ⅰ型单纯疱疹病毒(herpes simplex virusⅠ,简称HSV_1)引起的复发性角膜炎是一种重要致盲性眼病。而HSV_1在三叉神经节的潜伏感染则是单疱角膜炎复发的根源。虽然近代化疗药物及角膜移植术的应用能部分控制复发性病变,但对潜伏感染无效。本文的目的在于对近年有关这方面的研究资料做一概要复习,以供同道参阅。 Recurrent keratitis caused by herpes simplex virus I (HSV-1) is an important blinding eye disease. The latent infection of HSV_1 in the trigeminal ganglion is the root cause of the recurrence of herpes simplex keratitis. Although modern chemotherapy drugs and corneal transplantation can partially control the application of recurrent disease, but the latent infection is invalid. The purpose of this article is to review the relevant research materials in recent years for the purpose of reference.