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报告应用ＰＣＲ技术检测１３４例慢性肝病患者乙肝病毒ＤＮＡ的结果，并与乙肝五项进行了对比分析。结果显示，ＰＣＲ阳性率为６９．４％，乙肝五项阳性率为７６．１％，ＨＢｅＡｇ阳性率仅为１６．４％，ＨＢｅＡｇ阴性者仍有５９．８％为ＰＣＲ阳性。乙肝病毒感染后各种转归的病人ＰＣＲ阳性率为４８．０～８８．９％，抗体阳性的既往感染者ＰＣＲ也同样有效高的阳性率。结果提示，乙肝病毒感染后，不管是否有活动性肝病，均可有不同程度的病毒复制；ＨＢＶ－ＤＮＡ－ＰＣＲ检测在判断乙肝病毒复制方面比ＨＢｅＡｇ敏感得多，在乙肝病毒感染检出率方面不如乙肝五项敏感，两者结合才能全面而精确地判断乙肝病毒感染状态。
Report application of PCR detection of 134 cases of chronic liver disease in patients with hepatitis B virus DNA results, and five were compared with hepatitis B. The results showed that the positive rate of PCR was 69.4%, the positive rate of hepatitis B was 76.1%, the positive rate of HBeAg was only 16.4%, and that of HBeAg negative was 59.8%. The positive rate of PCR in all kinds of patients after the hepatitis B virus infection was 48.0-88.9%, and the positive rate of the PCR in the former antibody-positive patients was equally high. The results suggest that hepatitis B virus infection, with or without active liver disease, may have varying degrees of virus replication; HBV-DNA-PCR detection in determining hepatitis B virus replication is much more sensitive than HBeAg, hepatitis B virus infection in the detection rate Not as sensitive as hepatitis B five, both in order to comprehensively and accurately determine the status of hepatitis B virus infection.