不稳定型心绞痛,曾称急性冠状动脉功能不全,梗塞前心绞痛和中间型冠状动脉综合征。其临床特征为①新近(几个月内)发生的非劳力性心绞痛;②原有慢性稳定型心绞痛逐渐加重;③休息时或轻微活动诱发的心绞痛。心绞痛发作伴或不伴有心电图改变。其发展为急性心肌梗塞的发病率高,Mulcahy等(1981年)报告,在心绞痛出现后28天内非致死性心肌梗塞发病率为9％,此期间内病死率为4％,1年内病死率为10％。Luchi等(1987年)报告住院患者发生心肌梗塞率为12～17％。其病理生理学改变在多数病例中为阻塞性冠状动脉病变,伴血栓形成致冠状血流减少,冠状动脉痉挛也可能参与此过程。对冠状动脉行血管镜检查, Unstable angina, has called acute coronary insufficiency, pre-infarction angina and intermediate coronary syndrome. The clinical features of ① recent (within a few months) non-exertional angina; ② original chronic stable angina gradually aggravated; ③ rest or mild activity-induced angina. Angina pectoris with or without ECG changes. It developed a high incidence of acute myocardial infarction. Mulcahy et al. (1981) reported a 9% incidence of non-fatal myocardial infarction within 28 days of onset of angina and a 4% mortality during this period, with a 1-year case-fatality rate of 10%. Luchi et al. (1987) reported a 12-17% rate of myocardial infarction in hospitalized patients. The pathophysiological changes in most cases of obstructive coronary disease, with coronary thrombosis caused by coronary blood flow decreased, coronary spasm may also be involved in this process. Coronary artery vascular examination,