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目的探讨过敏性紫癜患儿外周血中性粒细胞与淋巴细胞的比值及嗜酸粒细胞对过敏性紫癜肾炎发生的预测价值,提高对可能发生不良并发症患儿的检出率,以便医务人员采取积极措施,降低患儿紫癜性肾炎的发生率。方法检测患儿入院时血清中性粒细胞,淋巴细胞,嗜酸粒细胞绝对值,并计算中性粒细胞与淋巴细胞比值。结果过敏性紫癜肾炎组中性粒细胞与淋巴细胞的比值(2.38±0.13)高于无肾损害组(1.80±0.15),紫癜肾炎组嗜酸粒细胞(0.35±0.66)较无肾损害组(0.07±0.07)明显升高,差异有统计学意义(P<0.01)。结论中性粒细胞与淋巴细胞的比值(N/L),嗜酸粒细胞对于过敏性紫癜肾炎有一定的预测价值。且比值越大紫癜性肾炎发生的可能性越大。
Objective To investigate the ratio of neutrophil to lymphocyte in peripheral blood and the predictive value of eosinophil in the development of Henoch-Schonlein purpura nephritis in children with Henoch-Schonlein purpura and to improve the detection rate of children with possible complications, Take active measures to reduce the incidence of purpura nephritis in children. Methods The absolute value of serum neutrophil, lymphocyte and eosinophil count at hospital admission was calculated, and the ratio of neutrophil to lymphocyte was calculated. Results The ratio of neutrophil to lymphocyte in allergic purpura nephritis group (2.38 ± 0.13) was higher than that in nephropathy group (1.80 ± 0.15), while the eosinophil granuloma in Purpura nephritis group (0.35 ± 0.66) 0.07 ± 0.07), the difference was statistically significant (P <0.01). Conclusions The ratio of neutrophils to lymphocytes (N / L) and eosinophils have some predictive value for allergic purpura nephritis. And the greater the ratio of purpuric nephritis, the greater the likelihood of occurrence.