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1982年,美国密歇根州和俄勒冈州暴发2起出血性结肠炎,患者的典型症状是严重腹绞痛、血性水样便、不发热或低热,最后证实病原体为大肠杆菌O_(157):H_7。同年12月,加拿大一所疗养院的353名人员中发生31例症状相似的腹泻,其病原体亦为大肠杆菌O_(157):H_7。这种大肠杆菌血清型在北美洲引起的暴发和其它散发病例的临床表现有其特殊性,引人注目。由大肠杆菌O_(157):H_7引起的出血性结肠炎患者,年龄在2岁～80岁,平均15岁,男女发病率相似。临床表现有腹泻(100%),少数为烂便,大多数为肉眼可见的血性水样泻;剧烈腹绞
In 1982, two outbreaks of hemorrhagic colitis occurred in the states of Michigan and Oregon. The typical symptoms of the patients were severe colic, bloody watery stools, no fever or fever. Finally, the pathogen was identified as Escherichia coli O_ (157): H_7. In December the same year, 31 out of 353 persons in a nursing home in Canada experienced similar symptoms of diarrhea. The pathogen was also Escherichia coli O_ (157): H_7. The clinical manifestations of the outbreaks and other sporadic cases of this Escherichia coli serotype in North America are remarkable and noticeable. The patients with hemorrhagic colitis caused by Escherichia coli O_ (157): H_7, aged from 2 to 80 years, with an average age of 15 years, had a similar incidence of men and women. Clinical manifestations of diarrhea (100%), a small number of rotten stools, most of the visible bloody watery diarrhea; severe abdominal heat