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目的探讨痰热清联合阿奇霉素治疗小儿支原体肺炎的临床疗效。方法将2010年2月—2011年6月于包头市中心医院就诊的106例支原体肺炎患儿随机分为联合治疗组53例和对照组53例,联合治疗组给予痰热清联合阿奇霉素治疗,对照组单用阿奇霉素静滴治疗,观察二组临床疗效、退热时间、咳嗽消失时间。结果联合治疗组痊愈32例(60.3%),显效18例(33.9%),有效2例(3.7%),无效1例(1.8%),总有效率98.0%;对照组痊愈23例(43.3%),显效10例(18.8%),有效8例(15.0%),无效12例(22.6%),总有效率77.3%。二组总有效率比较差异有统计学意义。联合治疗组总有效率高于对照组,P<0.05;咳嗽消失时间:联合治疗组(5.7±1.14)d,对照组(8.35±2.12)d,二组比较差异有统计学意义(t=2.5,P<0.05)。退热时间:联合治疗组(2.87±1.2)d,对照组(5.14±1.11)d,二组比较差异有统计学意义(t=2.557,P<0.05)。退热时间、咳嗽消失时间均短于对照组。结论痰热清联合阿奇霉素治疗小儿支原体肺炎疗效好,安全可靠。
Objective To investigate the clinical efficacy of Tanreqing combined with Azithromycin in the treatment of Mycoplasma pneumonia in children. Methods 106 patients with Mycoplasmal pneumonia who were treated in Baotou Central Hospital from February 2010 to June 2011 were randomly divided into combined treatment group (n = 53) and control group (n = 53). The combined treatment group was given Tanreqing combined with azithromycin, while the control group Group with azithromycin intravenous infusion of two groups were observed clinical efficacy, antipyretic time, cough disappear time. Results The combination therapy group cured 32 cases (60.3%), markedly effective in 18 cases (33.9%), effective in 2 cases (3.7%), ineffective in 1 case (1.8%), the total effective rate was 98.0% ), Markedly effective in 10 cases (18.8%), effective in 8 cases (15.0%), ineffective in 12 cases (22.6%), the total effective rate was 77.3%. The total effective rate of two groups was statistically significant difference. The total effective rate of the combination therapy group was higher than that of the control group, P <0.05; the disappearance time of the cough was 5.7 ± 1.14 days in the combination therapy group and 8.35 ± 2.12 days in the control group, with significant difference between the two groups (t = 2.5 , P <0.05). Antipyretic time: the combined treatment group (2.87 ± 1.2) d, the control group (5.14 ± 1.11) d, the difference between the two groups was statistically significant (t = 2.557, P <0.05). Antipyretic time, cough disappear time are shorter than the control group. Conclusion Tanreqing combined azithromycin treatment of children with mycoplasma pneumonia effective, safe and reliable.