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生长抑素广泛存在于中枢和外周神经系统， 参与了机体多种生理机能的活动和调节，在中枢神经系统中具有神经递质或神经调质的作用。生长抑素可增强海马的ＬＴＰ，促进学习与记忆； 临床一些痴呆症的认知和智力障碍与脑内生长抑素含量减少有关， 生长抑素能神经系统改变是Ａｌｚｈｅｉｍｅｒ’ｓ病的特异性致病机理之一。
Somatostatin is widely present in the central and peripheral nervous system, is involved in the activity and regulation of various physiological functions of the body, and plays a role of neurotransmitter or neuromodulator in the central nervous system. Somatostatin can enhance the LTP in the hippocampus and promote learning and memory. The clinical cognition and mental retardation of some dementias are related to the decrease of somatostatin content in the brain. The somatostatin nervous system changes are specific to Alzheimer’s disease One of the mechanisms of disease.