Seroprevalence of Helicobacter pylori infection among students of a Nigerian University

来源 :Asian Pacific Journal of Tropical Medicine | 被引量 : 0次 | 上传用户:wangligang987123
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Objective:To investigate the seroprevalence of Helicobacter pylori(H.pylori) infection among the undergraduate students of Nasarawa state University,Keffi,Nigeria.Methods:A total of 200 serum samples were collected from undergraduate students of Nasarawa State University, Keffi,and 100μL of each serum was aseptically transferred to the specimen well of an H.pylori antigen kit(Clinotech USA).The 2 distinctive red lines apearing in the control and test regions of the kit after 10 minufes indicated positive reaction.Results:Of the 200 students sampled, 108(54%) were seropositive.Analysis of seroprevalence of H.pylori revealed the correlation between infection prevalence and age.The infection prevalence was 45.5%among students aged 18-20,rose to the peak of 85.7%adults aged 31-40,dropped to 66.7%among those 41-50 years old,and continuously went down to 28.6%in the 51-year-old and above populaion.There was a statistically significant difference(using Chi-square) with respects to gender,age and type of infection(symptomatic or asymptomatic seropositive infection)(P<0.0S).Conclucions: Community Health Personnel should be aware of this microorganism as a potential cause of illness in children.Furthermore,the mode of transmission and possible means of controlling the bacterial infection among students or a community is of public health concern and requires further study. Objective: To investigate the seroprevalence of Helicobacter pylori (H.pylori) infection among the undergraduate students of Nasarawa state University, Keffi, Nigeria. Methods: A total of 200 serum samples were collected from undergraduate students of Nasarawa State University, Keffi, and 100 μL of each serum was aseptically transferred to the specimen well of an H. pylori antigen kit (Clinotech USA). The 2 distinctive red lines apearing in the control and test regions of the kit after 10 minufes indicated positive reaction. Results: Of the 200 students sampled, 108 (54%) were seropositive. Analysis of seroprevalence of H. pylori revealed the correlation between infection prevalence and age. infection prevalence was 45.5% among students aged 18-20, rose to the peak of 85.7% adults aged 31- 40, dropped to 66.7% among those 41-50 years old, and yet went down to 28.6% in the 51-year-old and above populaion. Where was statistically significant difference (using Chi-square) with respects to gender, age and type of infection (symptomatic or asymptomatic seropositive infection) (P <0.0S) .Conclucions: Community Health Personnel should be aware of this microorganism as a potential cause of illness in children .Furthermore, the mode of transmission and possible means of controlling the bacterial infection among students or a community is of public health concern and no further study.
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