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在非洲一些疟疾高发区很少应用镜检血片中的疟原虫作为抗疟治疗的依据。医务人员常根据母亲所述患儿有发热或有近期发热史即认为患儿可能患有疟疾而予以抗疟治疗。这种作法导致发热而无原虫血症的儿童也用抗疟药治疗。本文作者试图寻找更好的临床指征作为患病投药的指征,作者调查了1124名5岁以下的患儿在患病期间的症状和体症并测量腋温和肛温。体格检查包括检查患儿甲床苍白和脾脏肿大程度。指尖采血测血红蛋白浓度,厚血膜姬氏染色查疟原虫。对以上有关数据进行方差分析和多因素lo-gistic回归分析。
Malaria parasites in microscopic examination of blood films are rarely used as a basis for anti-malarial treatment in some malaria-prone areas in Africa. Medical staff are often given anti-malarial treatment on the basis of the children’s fever or recent fever history that the child may have malaria. This practice has led to the use of antimalarial drugs in children who are feverish and have no parasitemia. The authors sought to find better clinical indications as an indication of ill-treatment, investigating the symptoms and signs of disease in children under 5 years old during the illness and measuring axillary and rectal temperatures. Physical examination includes examination of children with pale bed and spleen enlargement. Fingertip blood test hemoglobin concentration, thick blood Ji Jiasi staining check malaria parasite. The above data were analyzed by ANOVA and multivariate logistic regression analysis.