论文部分内容阅读
为探讨晚期上颌窦癌的合理治疗方法。对１３２例晚期上颌窦癌分别行放疗、放疗加手术和手术加放疗的患者进行分析。用寿命表法及ｋａｐｌａｎ－ｍｅｉｅｒ计算生存率。单放组和综合组５ａ生存率分别是２４．８５％和４５．６３％，综合组明显好于单放组。单放组中Ｄｔ≥７０Ｇｙ５ａ生存率显著高于Ｄｔ＜７０Ｇｙ。综合组中眶底受侵者行眶挖术或保存眼球者５ａ生存率类似（Ｐ＞０．７５）。对Ｎ０（颈部无淋巴结转移）未行颈部处理者，鳞癌颈部转移率为１５．５８％。结论：晚期上颌窦癌以综合治疗为佳。单纯放疗总剂量不应低于７０Ｇｙ。对大多数患者来说，眶底受侵经综合治疗可以保住眶内容物，其生存率将不产生影响。对Ｎ０的上颌窦癌患者不支持预防性颈照射
To explore the reasonable treatment of advanced maxillary sinus cancer. 132 cases of advanced maxillary sinus cancer were treated with radiotherapy, radiotherapy plus surgery and surgery plus radiotherapy patients were analyzed. Use life table method and kaplan-meier to calculate the survival rate. The survival rates of radiotherapy group and comprehensive group 5a were 24.85% and 45.63%, respectively. The comprehensive group was significantly better than the single radiotherapy group. The survival rate of Dt≥70Gy5a was significantly higher than that of Dt <70Gy. The combined group of orbital floor invaders orbital excavation or preservation of the ocular 5a survival rate was similar (P> 0.75). For N0 (cervical lymphatic metastasis) without neck treatment, squamous cell carcinoma of the neck metastasis rate was 15.58%. Conclusion: The treatment of advanced maxillary sinus cancer is better. The total dose of radiotherapy alone should not be less than 70Gy. For most patients, combined treatment of orbital floor invasion can hold the orbital contents, the survival rate will not have an impact. Patients with N0 maxillary sinus cancer do not support prophylactic neck irradiation