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应用GFAP及Vimentin(ABC法)对26例星形细胞瘤进行免疫组化分析。结果显示所有星形细胞瘤均呈GFAP,VIM阳性表达。GFAP阳性细胞数与病理学分级呈负相关,组织学分级高分化差的星形细胞瘤,阳性级别低。而VIM表达与组织学分级无相关。GFAP阳性表达对星形胶质细胞瘤的恶性程度及指导临床治疗有重要价值。
GFAP and Vimentin (ABC method) were used to analyze 26 cases of astrocytomas by immunohistochemistry. The results showed that all astrocytoma showed GFAP, VIM positive expression. The number of GFAP-positive cells was negatively correlated with the pathological grade, histological grades were poorly differentiated astrocytomas, and the positive levels were low. There was no correlation between VIM expression and histological grade. The positive expression of GFAP is of great value to the malignancy of astrocytoma and to guide clinical treatment.