多塞平(doxepin)属于三环抗抑郁药,它除了有类似阿托品的周围抗胆碱作用、阻断毒蕈碱受体、解除平滑肌、膈肌痉挛、抗呃逆作用外,还有中枢抗胆碱作用和中枢镇静作用。吾院用多塞平治疗老年顽固性呃逆4例,效果良好,报道于下。例1 男,76yr,以右半身无力失语1yr,频繁呃道3d为主诉入院。1yr前患高血压脑出血遗留右侧偏瘫失语,恢复期时发生呃逆,服多塞平2d(150mg/d)后停止。本次入院时,经体检和头 Doxepin is a tricyclic antidepressant. Apart from the anticholinergic effect of atropine, blocking muscarinic receptors, releasing smooth muscle, diaphragmatic muscle spasm and anti-hiccup, central anticholinergic Role and central sedation. My hospital with doxepin treatment of elderly refractory hiccups in 4 cases, the effect is good, reported in the next. Example 1 male, 76yr, right aphasia aphasia 1yr, frequent uh Road 3d main admission. 1yr suffering from hypertensive cerebral hemorrhage left hemiplegia left right, hiccups occurred during convalescence, taking doxepin 2d (150mg / d) after the stop. The admission, the physical examination and head