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目的观察匹多莫德辅治新生儿感染性肺炎对患儿血清降钙素原(PCT)、C反应蛋白(CRP)和白细胞(WBC)水平的影响。方法将206例新生儿感染性肺炎患儿随机分为观察组和对照组各103例。对照组患儿给予常规治疗,观察组在此基础上给予匹多莫德口服治疗。比较2组患儿治疗前后血清PCT、CRP、WBC水平变化。结果2组患者治疗后血清PCT、CRP、WBC水平均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论匹多莫德辅治新生儿感染性肺炎能显著改善患儿血清PCT、CRP、WBC的水平,效果优于单纯常规治疗,值得推广应用。
Objective To observe the effects of pidotimod on neonatal infectious pneumonia on serum levels of procalcitonin (PCT), C-reactive protein (CRP) and white blood cells (WBC) in children. Methods A total of 206 neonates with infectious pneumonia were randomly divided into observation group (n = 103) and control group (n = 103). The control group of children given conventional treatment, the observation group on this basis to give podolactone oral treatment. The changes of serum PCT, CRP and WBC in two groups before and after treatment were compared. Results The levels of serum PCT, CRP and WBC in the two groups after treatment were lower than those before treatment, and the difference between the two groups was statistically significant (P <0.05). Conclusion Pidotimod can effectively reduce the levels of serum PCT, CRP and WBC in infants with adjuvant neonatal pneumonia, which is better than simple routine therapy and should be widely applied.