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作者利用端粒酶原位显示技术检测大肠癌和相应癌旁正常粘膜组织中端粒酶活性，旨在探讨端粒酶活性与大肠癌的关系，为大肠癌早期诊断和治疗提供借鉴。1材料与方法1．1标本收集本校附属湘雅医院及附二医院大肠癌手术切除标本40例及20例相应癌旁正常上皮粘膜（距肿瘤边缘10cm以上
The authors used telomerase in situ display technology to detect telomerase activity in colorectal cancer and corresponding adjacent normal mucosa, in order to explore the relationship between telomerase activity and colorectal cancer, and provide reference for early diagnosis and treatment of colorectal cancer. 1Materials and methods 1.1 Specimen collection 40 cases of colorectal cancer resection specimens from Xiangya Hospital and Second Affiliated Hospital of the University and 20 cases of corresponding normal epithelial mucosa (more than 10cm from the edge of tumor).