Alternative models for transgenerational epigenetic inheritance:Molecular psychiatry beyond mice and

来源 :世界精神病学杂志 | 被引量 : 0次 | 上传用户:wzy_shun
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Mental illness remains the greatest chronic health burden globally with few inroads having been made despite significant advances in genomic knowledge in recent decades.The field of psychiatry is constantly challenged to bring new approaches and tools to
其他文献
复杂目标在高频区具有多散射中心特性,而目前针对车载毫米波雷达的射频仿真测试多以点目标仿真为主,仿真精度较低。对此,通过分析复杂目标的多散射中心特性,提出基于体目标雷达截面积的毫米波雷达道路场景仿真方法。这一方法通过体目标雷达截面积的预估和位姿信息的计算,对特定场景下的多散射点位姿序列进行求解,实现道路场景仿真要求。基于场景实例对这一方法的可行性进行了验证。
针对重卡轮毂轴承在制造过程中容易出现的各种异常现象,设计了一套应用于生产线的重卡轮毂轴承在线振动检测系统。这一系统包括机械和测控两部分,机械部分由进出料、传感器、驱动装置、加载装置等组成,测控部分包括基于可编程序控制器的动作控制和基于LabVIEW软件的数据分析处理。抽取100套轴承进行检测,检测准确率为98%,由此验证了这一系统的准确性和可靠性。
Psychiatric disorders,including suicide,are complex disorders that are affected by many different risk factors.It has been estimated that genetic factors contribute up to 50%to suicide risk.As the candidate gene approach has not identified a gene or set o
Yoga is considered a widely-used approach for health conservation and can be adopted as a treatment modality for a plethora of medical conditions,including neurological and psychological disorders.Hence,we reviewed relevant articles entailing various neur
It is necessary to find a mechanism that generates first-person inner sensation of pleasure to understand what causes addiction and associated behaviour by drugs of abuse.The actual mechanism is expected to explain several disparate findings in nucleus ac
Chronic use of antipsychotic medications entails a dilemma between the benefit of alleviating psychotic symptoms and the risk of troubling,sometimes lifeshortening adverse effects.Antipsychotic-induced cardiotoxicity is one of the most life-threatening ad
In December 2019,a novel coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)was initially reported in Wuhan,China.Previous epidemics including SARS and middle east respiratory syndrome raises concern tha
BACKGROUND Empathy has long been considered a multidimensional construct,encompassing cognitive,affective and behavioral domains.Deficits in empathic competences in early childhood contribute to psychopathology,and have been variably implicated in several
BACKGROUND Chronic insomnia affects about 6%-13% of the Canadian population.Although treatments already exist,they each have their own issues.Neurofeedback is a neuromodulation technique that specifically targets abnormal brain activity and is gaining att
Dopaminergic neurotoxicity is characterized by damage and death of dopaminergic neurons.Parkinson\s disease(PD)is a neurodegenerative disorder that primarily involves the loss of dopaminergic neurons in the substantia nigra.Therefore,the study of the mec