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目的了解武汉市孕妇B族链球菌(GBS)感染的流行病学调查及与妊娠结局的关系。方法对2013年3月1日-2014年7月1日住院分娩的患者进行筛查,查出GBS阳性者72例为研究组,同期住院分娩的阴性患者252例为对照组,研究两组间早产、胎膜早破、产褥感染的发生差异,同时观察新生儿出生Apgar评分、新生儿肺炎、新生儿缺血缺氧性脑病的发生,采用电话回访的方式追踪新生儿出生后患病情况及成长状况。结果检查患者1 458例,查出GBS阳性72例,阳性率4.9%,两组间在胎膜早破的发生上有统计学差异(P<0.01),在早产、产褥病率、新生儿肺炎、新生儿缺血缺氧性脑病的发生上差异有统计学意义。结论 GBS的发生可对母婴妊娠结局造成影响,应在有条件的地区普及GBS筛查。
Objective To understand the epidemiological investigation of pregnant group B streptococcus (GBS) in Wuhan and its relationship with pregnancy outcome. Methods From March 1, 2013 to July 1, 2014, hospitalized patients were screened. Among them, 72 patients with GBS positive were selected as the study group, while 252 patients with negative GBS during the same period were selected as the control group. Premature labor, premature rupture of membranes and puerperal infection were observed. At the same time, the incidence of newborns’ Apgar score, neonatal pneumonia and neonatal hypoxic-ischemic encephalopathy were observed. The incidence of postnatal morbidity was tracked by telephone And growth status. Results A total of 1 458 patients were examined. 72 cases were found positive for GBS, the positive rate was 4.9%. There was a significant difference in the incidence of premature rupture of membranes between the two groups (P <0.01). Premature labor, puerperal morbidity, Pneumonia, neonatal hypoxic-ischemic encephalopathy occurred statistically significant differences. Conclusion The occurrence of GBS may have an impact on the pregnancy outcome of mothers and infants, and GBS screening should be popularized in the conditional areas.