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目的 分析腹腔镜下胰体尾切除术(LDP)术后胰瘘的危险因素.方法 回顾性分析50例行LDP患者的临床资料,行单因素及多因素Logistic回归分析术后发生胰瘘的危险因素.结果 LDP术后胰瘘发生率为22.00%(11/50).单因素分析结果显示,术前合并低蛋白血症会影响LDP术后胰瘘的发生(P<0.05).多因素Logistic回归分析结果显示,术前低蛋白血症和胰腺质地较软为胰瘘发生的独立危险因素(P<0.05).结论 对于术前低蛋白血症患者应及时纠正蛋白水平,对于胰腺质地较软的患者应选择恰当的手术方式,以减少LDP术后胰瘘的发生.“,”Objective To analyze the risk factors for pancreatic fistula after laparoscopic distal pancreatectomy .Methods The clinical data of 50 patients underwent laparoscopic distal pancreatectomy were retrospectively analyzed .The risk factors for pancreatic fistula after surgery were analyzed .Results The incidence rate of pancreatic fistula after laparoscopic distal pancreatectomy was 22.00% .The univariate analysis showed that preoperative hypoalbuminemia affected the incidence of pancreatic fistula after surgery (P<0 .05) .The multivariate logistic regression analysis showed that preoperative hypoalbuminemia and softer pancreas were the independent risk factors for pancreatic fistula(P<0 .05) .Conclusion To reduce the occurrence of pancreatic fistula after laparoscopic distal pancreatectomy ,attention should be paid to correcting blood protein level in time in the patients with preoperative hypoalbuminemia and selecting appropriate surgery method for those with softer pancreas .