目的:探讨巴马小型猪脾虚痰浊证模型的造模与评价方法,并观察模型持续时间。方法:选取9月龄雄性去势普通级小型猪8只,施以每日冲刺跑步训练联合高脂单笼饲养干预,造模中每日对巴马小型猪进行模型评分(包括:等待喂食行为、皮毛色泽、口色、粪便性状);并分别测量生命体征(耳温、心率、呼吸频率、收缩压、舒张压)及形体指标(体质量、体长、腹围、臀宽)。结果:高脂单笼饲养联合跑步干预4周后,小猪开始有脾虚痰浊证的表现:等待喂食变得反应淡漠,粪便稀溏;第8周时,等待进食行为淡漠、皮毛不泽、口色淡白、粪便稀溏,具备了脾虚痰浊证模型表现,模型评分明显高于造模前(P<0.05)且趋于稳定。停止跑步干预后,高脂单笼饲养至第14周时,小猪脾虚痰浊证表现持续存在,但粪便变成球形便。形体指标显示脾虚痰浊模型小猪生长迅速,较同月龄正常小猪明显肥胖。冲刺跑步造模期内,小猪的耳温增高、呼吸频率增快;停止跑步后,耳温下降、呼吸减慢。造模期内,小猪心率、血压未见明显变化。但脾虚痰浊模型小猪耳温、呼吸、心率、血压,明显高于同月龄正常小猪,提示脾虚痰浊模型小猪处于高代谢状态。结论:疲劳过度联合高脂单笼饲养4周后,小猪开始出现脾虚痰浊证表现,造模8周后成功复制小猪脾虚痰浊证模型,且模型持续时间至少6周。 Objective: To investigate the modeling and evaluation of the phlegm and phlegm syndrome of spleen deficiency type in Bama miniature pig and to observe the duration of the model. Methods: Eight male castration general-aged pigs at 9 months of age were selected and fed with daily sprint running training and high-fat single-cage feeding. Bam mini-pigs were scored daily on the model (including waiting for feeding behavior , Fur color, mouth color and stool characteristics). The vital signs (ear temperature, heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure) and physical indicators (body weight, body length, abdominal circumference and hip width) were measured. Results: After 4 weeks of high-fat single-cage feeding combined with running, the piglets began to show symptoms of phlegm and phlegm-damaging syndrome of the spleen: waiting for feeding became indifferent and stool was thinner; at the 8th week, Pale in color and thin in stool. It possessed the phlegm phlegm syndrome model of spleen deficiency. The model score was significantly higher than that before modeling (P <0.05) and tended to be stable. Stop running after intervention, high-fat single cage feeding until the 14th week, piglets spleen deficiency phlegm syndrome persists, but the stool becomes spherical. Physical indicators show that spleen deficiency phlegm turbidity model piglets grow rapidly, compared with the same age of normal piglets obviously obese. Sprint run modeling period, the pig’s ear temperature increased respiratory rate increased; stop running, the ear temperature drops, breathing slows down. Modeling period, pig heart rate, blood pressure no significant change. However, the ear temperature, respiration, heart rate and blood pressure of piglets with phlegm-turbidity model were significantly higher than those of normal piglets of the same age, suggesting that piglets with phlegm-phlegm-turbidity model were in a high metabolic state. CONCLUSION: Pigs started to show phlegm and phlegm-resolving phlegm syndrome after 4 weeks of over-fatigation combined with high-fat single cage. The model of phlegm and phlegm-resolving phlegm of spleen deficiency was successfully replicated 8 weeks after the model was established, and the model lasts for at least 6 weeks.