对41例肺炎患儿进行了血清肌酸磷酸激酶(CPK)、乳酸脱氢酶(LDH)及其同功酶的测定。结果表明肺炎患儿CPK及LDK活性均有明显升高,其阳性率分别为75.60％及68.29％。二者在肺炎心衰组与无心衰组间无差异(P>0.05)。LDH_1阳性率在心衰组为59.09％,无心衰组为26.32％,两组间差异有显著意义(P<0.05)。同功酶测定结果显示了较明显的组织特异性,对肺炎合并心肌损害的判断有意义。 41 cases of children with pneumonia serum creatine phosphokinase (CPK), lactate dehydrogenase (LDH) and its isozyme determination. The results showed that the CPK and LDK activity of children with pneumonia were significantly increased, the positive rates were 75.60% and 68.29%. There was no difference between the two groups (P> 0.05). The positive rate of LDH - 1 was 59.09% in heart failure group and 26.32% in heart failure - free group, with significant difference between the two groups (P <0.05). Isozyme assay results showed that the more obvious tissue-specific, the diagnosis of myocardial damage with pneumonia is meaningful.