wegener氏肉芽肿系罕见病种,表现为上、下呼吸道坏死性肉芽肿损害,合并局灶性坏死性肾小球性肾炎、小动静脉急性脉管炎和肉芽肿性病变,侵犯心脏的病例更属罕见,我们见到一例,现报道如下。患者,女,26岁,因双侧鼻阻、溢血性脓涕,伴发热、头痛三个月入院,门诊曾行鼻粘膜活检为寻常狼疮。体检:T38.2℃,消瘦,心率100次/分,律齐,心前区闻及Ⅱ级SM,两 Wegener’s granulomatosis rare cases of disease, manifested as upper and lower respiratory necrosis granulomatous lesions with focal necrotic glomerulonephritis, acute arteritis and granulomatous small artery lesions, cases of heart violations Even more rare, we see an example is reported below. Patients, female, 26 years old, due to bilateral nasal resistance, purulent nasal discharge, fever, headache three months admitted to the clinic had nasal mucosa biopsy as usual lupus. Physical examination: T38.2 ℃, weight loss, heart rate 100 beats / min, law Qi, heart area and grade Ⅱ SM, two