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白细胞三烯(leucotriene LT)C_4、D_4及E_4是花生四烯酸经脂氧合酶代谢途径的产物,具有类慢反应物质的作用,能引起支气管收缩,呼吸道上皮纤毛运动频率减少,使皮肤血管扩张而致水肿。在鼻过敏反应过程中鼻分泌物中存在这类物质,但其病理怍用不明,本文通过测定鼻粘膜血流、鼻气道阻力(NAR)及鼻分泌物研究LTD_4在鼻过敏反应中的作用。
Leucotriene LT C_4, D_4 and E_4 are products of arachidonic acid which are metabolized by the lipoxygenase. They act as slow-acting substances and cause bronchoconstriction and decrease the frequency of cilia movement in the respiratory epithelium. Expansion caused by edema. In the process of nasal allergic reaction of nasal secretions in the presence of such substances, but its pathological unclear, in this paper by measuring the nasal mucosal blood flow, nasal airway resistance (NAR) and nasal secretions study LTD_4 role in nasal allergic reactions .