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目的探讨正常形态精子百分率与处理后前向运动精子总数达标率的关系及其对宫腔内人工授精临床妊娠率的影响。方法行夫精宫腔内人工授精的426对不孕夫妇(563个周期),依据正常形态精子百分率分为3组,正常形态精子百分率<4%为A组,≥4%~15%为B组,>15%为C组,比较各组精液处理后前向运动精子总数达标率及对宫腔内人工授精临床妊娠率。结果 A组精液处理后前向运动精子总数达标率低于B、C组(P<0.05),B组低于C组(P<0.05);A组周期妊娠率(7.77%)明显低于B、C组(16.21%、18.05%)(P<0.05)。结论正常形态精子百分率对精液处理后前向运动精子总数达标率有明显影响,二者共同影响宫腔内人工授精结局;正常形态精子百分率≥4%可获较高临床妊娠率。
Objective To investigate the relationship between the percentage of spermatozoa with normal morphology and the compliance rate of total sperm motility after treatment and its effect on clinical pregnancy rate of intrauterine insemination. Methods 426 infertile couples (563 cycles) with intrauterine insemination were divided into 3 groups according to the percentage of normal spermatozoa. The percentage of normal spermatozoa was <4% in group A and ≥4% to 15% in group B ,> 15% for the C group, compared the rate of sperm motility sperm up to the standard and the clinical pregnancy rate of intrauterine insemination. Results The standard of sperm motility in group A after semen treatment was lower than that in group B and C (P <0.05), that in group B was lower than that in group C (P <0.05), and that in group A was significantly lower than that in group B , C group (16.21%, 18.05%) (P <0.05). Conclusion The percentage of normal spermatozoa has a significant effect on the rate of sperm motility of spermatozoa after the sperm are treated, both of which affect the results of intrauterine insemination. The percentage of normal spermatozoa is higher than 4% and the higher clinical pregnancy rate can be obtained.