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目的探讨在不同的空腹三酰甘油(TG)水平的人群中心肌梗死(MI)的发生情况及其高危影响因素。方法以2006年6月至2007年10月开滦煤矿集团健康体检的在职和离退休职工为研究对象(n=100 271),根据不同TG水平,将研究人群分为:TG1组(0.0125kg/m2,空腹血糖(FBG)≥6.1mmol/L,高密度脂蛋白胆固醇(HDL-C)<1.5mmol/L等均为发生MI的危险因素(P<0.05)。Cox比例风险回归模型显示,校正性别、年龄等因素后,随着TG水平的升高,发生MI的相对危险亦增加。结论在研究的开滦人群中,空腹TG水平升高者MI发生风险显著增加,而年龄、BMI、FBG和HDL-C是空腹TG水平升高人群发生MI的危险因素。
Objective To investigate the incidence of myocardial infarction (MI) and its risk factors in different fasting triglyceride (TG) populations. Methods The current and retired workers in Kailuan Coal Mine Group from June 2006 to October 2007 were enrolled in this study (n = 100 271). According to different levels of TG, the study population was divided into: TG1 group (0.01 25kg / m2, fasting blood glucose (FBG) ≥6.1mmol / L, high density lipoprotein cholesterol (HDL-C) mmol / L were the risk factors for occurrence of MI (P <0.05). Cox proportional hazards regression model showed that after adjusting for gender, age and other factors, the relative risk of developing MI increased with the increase of TG level. Conclusions In the study population of Kailuan, there was a significant increase in the risk of developing MI in fasting TG levels, while age, BMI, FBG and HDL-C were risk factors for MI in fasting TG patients.