首次报道了甲醛衍生的胺缩醛和芳基硼酸在水的促进下,可以在没有催化剂的条件下高效的合成三级胺.在此基础上建立了一种利用多聚甲醛,二级胺和芳基或杂环硼酸合成三级胺的高效合成方法.此反应条件温和,操作简单,具有很好的底物适应性,目标产物的收率最高可达93%. For the first time, formaldehyde-derived amine acetals and arylboronic acids were reported to be able to efficiently synthesize tertiary amines in the absence of a catalyst under the promotion of water. On the basis of this, a novel method of using paraformaldehyde, secondary amines and Aryl or heterocyclic boronic acid synthesis of tertiary amine high efficiency synthesis method. The reaction conditions are mild, easy to operate, has good substrate adaptability, the yield of the target product up to 93%.