几种药物配成一种制剂或几种制剂混合给药,各药之间由于直接产生物理或化学的变化,而使药效或毒性发生质和量的变化,则属于药剂学上的配伍变化或配伍禁忌。在药物治疗中常需同时或在短期内先后应用两种或更多种药物于病人,称为联合用药,联合用药的目的是为了增强疗效、减少耐药性、纠正不良反应或付作用,或是为了分别治疗不同症状及合并症等。联合用药时在体内各药物之间可能发生相互影响,使它们的作用、治疗效果以及不良反应起了质或量的变化,则属于药理学上的配伍变化,称为药物作用的相互影响,也有简称为 Several drugs dubbed a preparation or a mixture of several formulations, due to the direct physical or chemical changes between the various drugs, and the efficacy or toxicity occur qualitative and quantitative changes, which belongs to the pharmaceutical compatibility changes Or incompatibility. It is often necessary to administer two or more drugs to patients in the concurrent or short-term use of the drug, often referred to as combination therapy, for the purpose of enhancing efficacy, reducing drug resistance, correcting adverse effects or adverse effects, or In order to treat different symptoms and complications, respectively. Combination of drugs in the body may occur between the mutual influence, so that their role, treatment and adverse reactions played a qualitative or quantitative changes, the pharmacological compatibility changes, known as the interaction of drug effects, there are Referred to as