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目的通过了解扬州市城区出生缺陷发生情况的分析,了解出生缺陷的动态变化和现状。方法回顾性分析2011年10月1日至2015年9月30日扬州市城区分娩机构上报的所有缺陷儿病例登记卡资料。结果扬州市2012~2015年城区围产儿共60 222例,共发现缺陷儿650例,缺陷发生率为10.79‰;<28w治疗性引产率呈逐年上升趋势;围产儿出生缺陷发生率经产前诊断治疗性引产后由原来的10.79‰降至8.14‰。结论产前筛查和产前诊断可及时发现某些严重的出生缺陷疾病,为孕妇提供终止病理妊娠的机会,从而有效地提高出生人口的质量。
Objective To understand the occurrence and development of birth defects in urban areas of Yangzhou and to understand the dynamic changes and current status of birth defects. Methods A retrospective analysis of registration data of all cases of defective children reported by the delivery organizations in the city of Yangzhou from October 1, 2011 to September 30, 2015 was retrospectively analyzed. Results There were 60,222 perinatal infants in urban area from 2012 to 2015 in Yangzhou City. A total of 650 cases of defective children were found, the incidence of defects was 10.79 ‰. The therapeutic induction rate of <28 weeks was increasing year by year. The incidence of perinatal birth defects was estimated by prenatal diagnosis Therapeutic induced abortion decreased from the original 10.79 ‰ to 8.14 ‰. Conclusion Prenatal screening and prenatal diagnosis can promptly identify some serious cases of birth defects and provide pregnant women with the opportunity to stop the pathological pregnancy so as to effectively improve the quality of the birth population.