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目的探讨导致结直肠癌术后局部复发的可能因素。方法将结直肠癌术后局部复发33例与无复发31例的临床及病理资料进行对比分析。结果直肠癌局部复发22例,占67%(P<005)。Miles术后局部复发6例,占27%,Dixon术后复发16例占73%(P<001)。术后正规化学药物治疗或放射治疗与非治疗者比较差异有显著意义。结论结直肠癌发生的部位、手术方式、淋巴结清扫程度及术后正规化学药物治疗或放射治疗是影响其术后局部复发的因素。
Objective To investigate the possible causes of local recurrence after colorectal cancer surgery. Methods The clinical and pathological data of 33 patients with local recurrence of colorectal cancer and 31 patients without recurrence were analyzed and compared. Results There were 22 cases of local recurrence of rectal cancer, accounting for 67% (P<005). Miles had local recurrence in 6 cases, accounting for 27%. Recurrence of Dixon in 16 cases accounted for 73% (P<001). There was a significant difference between regular chemotherapy or radiotherapy and non-treatment. Conclusions The location of colorectal cancer, the surgical method, the degree of lymph node dissection, and postoperative regular chemotherapy or radiotherapy are the factors affecting the postoperative local recurrence.