论文部分内容阅读
目的探讨血糖水平和颈动脉粥样硬化与缺血性脑血管病的相关性,为预防和治疗缺血性脑血管病提供一定指导。方法选取2010年6月至2012年6月我院收治的糖尿病患者94例,根据颈动脉有无斑块和IMT情况,随机分为两组,A组54例伴颈动脉硬化,B组40例无颈动脉硬化,选取同期正常者30例作为C组,观察三组IMT、HbA1c、MAGE、DMMG和BGFC、脑梗死的复发率及血糖水平和颈动脉粥样硬化与缺血性脑血管病的相关性。结果 A、B两组HbA1c与IMT明显高于C组,A、B两组之间也有显著差异,存在统计学意义(P<0.05);A、B两组在MAGE、DMMG和BGFC上明显高于C组,且A、B两组也具有显著差异,存在统计学意义(P<0.05);A、B、C三组间脑梗死复发率具有显著差异,存在统计学意义(P<0.05);MAGE、BGFC与IMT的存在密切相关(P<0.05),颈动脉粥样硬化与脑梗死复发存在相关关系(P<0.05)。结论血糖波动是促进颈动脉硬化的相关因素,颈动脉粥样硬化与脑梗死复发密切相关,其严重程度决定着脑梗死复发的几率,因而血糖波动水平与脑梗死复发存在相关性。
Objective To investigate the correlation between blood glucose level and carotid atherosclerosis and ischemic cerebrovascular disease and to provide some guidance for the prevention and treatment of ischemic cerebrovascular disease. Methods From June 2010 to June 2012, 94 cases of diabetic patients admitted to our hospital were randomly divided into two groups according to whether carotid artery plaque and IMT were present. A group of 54 patients with carotid atherosclerosis, B group of 40 patients No carotid atherosclerosis, 30 normal subjects were selected as group C, the three groups were observed IMT, HbA1c, MAGE, DMMG and BGFC, the recurrence rate of cerebral infarction and blood glucose levels and carotid atherosclerosis and ischemic cerebrovascular disease Correlation. Results The levels of HbA1c and IMT in groups A and B were significantly higher than those in group C, with significant differences between groups A and B (P <0.05). The levels of MAGE, DMMG and BGFC were significantly higher in groups A and B There was significant difference between group A and C (P <0.05). There was significant difference between group A, B and C (P <0.05) ; MAGE, BGFC and IMT were closely related (P <0.05). There was a correlation between carotid atherosclerosis and recurrent cerebral infarction (P <0.05). Conclusion The fluctuation of blood glucose is a related factor to promote carotid atherosclerosis. Carotid atherosclerosis is closely related to the recurrence of cerebral infarction. The severity of the disease determines the risk of recurrent cerebral infarction. Therefore, the level of blood glucose fluctuation correlates with the recurrence of cerebral infarction.