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目的:分析南京市成人居民不同血糖代谢与血脂异常的关联性。方法:2017年1月—2018年6月,采用五阶段分层整群随机抽样方法,开展南京市慢性病及其危险因素监测,共调查了61 098例18岁及以上社区常住居民。调查内容包括问卷调查、身体测量和实验室检测。采用复杂加权和多水平模型探讨不同血糖代谢与血脂异常间关联。结果:最终纳入 60 283例。正常血糖、糖尿病前期、糖尿病患者比例标化值分别为71.2%、17.9%和10.9%,血脂异常的患病率、知晓率、治疗率、控制率标化值分别为29.8%、41.6%、28.9%、22.9%,血脂异常合并糖尿病比例为52.9%。正常血糖组、糖尿病前期、糖尿病人群血脂异常标化患病率逐渐增高,分别为24.0%、38.8%和52.9%(n P<0.001)。多水平模型分析显示,与血糖正常组相比,糖尿病前期(n OR=2.04,95%n CI:1.95~2.13)、糖尿病组(n OR=3.87,95%n CI:3.66~4.10)罹患血脂异常的风险均呈上升趋势(均n P<0.001)。随着血糖水平的增加,正常血糖组、糖尿病前期、糖尿病人群的血脂异常知晓率(36.3%、42.8%和56.2%)、治疗率(23.7%、29.2%和43.7%)、控制率(20.4%、22.6%和30.1%)也逐渐增加(均n P<0.001)。n 结论:血脂异常和糖尿病是南京市居民两种主要慢性病,两者间存在相关性。“,”Objective:To explore the association between different paths of diabetic progression and dyslipidemia in a Nanjing adult population.Methods:From January 2017 to June 2018, 61, 098 local residents aged ≥18 years were selected from the Chronic Disease and Risk Factor Surveillance database in Nanjing using a five-stage stratified cluster random sampling method. Data were collected through interview surveys, physical measurements, and laboratory examinations. The relationship between different rates of diabetic progression and dyslipidemia was analyzed using complex weighting and multilevel models.Results:In all, 60, 283 participants were finally enrolled in the study. The weighted proportions of normal glucose regulation, pre-diabetes, and diabetes were 71.2%, 17.9%, and 10.9%, respectively. The overall weighted prevalence, awareness, treatment, and control of dyslipidemia were 29.8%, 41.6%, 28.9%, and 22.9%, respectively. The weighted proportion of patients with dyslipidemia combined with diabetes was 52.9%. The weighted prevalence of dyslipidemia in adults with normal glucose regulation, pre-diabetes, and diabetes was 24.0%, 38.8%, and 52.9%, respectively (all n P<0.001). Compared to the normal glucose regulation group, subjects with pre-diabetes (n OR = 2.04, 95%n CI: 1.95-2.13) or diabetes (n OR= 3.87, 95%n CI: 3.66-4.10) had possibly gradually increased risks of dyslipidemia (all n P<0.001). In addition, there was an increasing trend toward awareness, treatment, and control of dyslipidemia with increasing levels of glucose (alln P<0.001). The weighted awareness of dyslipidemia in adults with normal glucose regulation, pre-diabetes, and diabetes was 36.3%, 42.8%, and 56.2%, respectively; the corresponding rates of treatment and control were 23.7%, 29.2%, and 43.7%, and 20.4%, 22.6%, and 30.1%, respectively.n Conclusion:Diabetes and dyslipidemia have become the main chronic diseases in the Nanjing population.