亮丙瑞林微球蛋白应用于子宫肌瘤的临床效果

来源 :深圳中西医结合杂志 | 被引量 : 0次 | 上传用户:urtracy2009
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目的:探讨亮丙瑞林微球蛋白应用于子宫肌瘤的临床效果.方法:将福建中医药大学附属晋江中医院2019年12月至2021年2月期间收治的132例子宫肌瘤患者,按照随机数字表法分为对照组与观察组,各66例.对照组直接给予手术治疗,观察组于术前3个月及术后给予亮丙瑞林微球蛋白治疗,观察两组治疗效果、性激素水平、血清激素水平及药物不良反应.结果:治疗后观察组总有效率(95.45%)高于对照组(78.79%),差异具有统计学意义(P<0.05).观察组患者的促黄体生成素(LH)、孕激素、促卵泡生成素(FSH)、雌二醇、人绒毛膜促性腺激素(HCG)、LH/FSH均低于对照组,差异具有统计学意义(P<0.05).治疗后观察组患者的内皮生长因子(VEGF)、胰岛素样生长因子(IGF-1)、超敏C反应蛋白(hs-CRP)水平均低于对照组,差异具有统计学意义(P0.05).结论:亮丙瑞林微球蛋白应用于子宫肌瘤治疗可有效改善性激素水平,降低hs-CRP、VEGF、IGF-1水平,提高临床治疗效果,且不增加药物不良反应.
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