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目的探讨多囊卵巢综合征子宫内膜增生患者的临床特点。方法采用前瞻性研究方法,对76例多囊卵巢综合征患者进行子宫内膜病理检查,闭经时间、体重指数调查,血清葡萄糖、胰岛素、性激素水平测定及行阴道超声子宫内膜厚度测量。结果76例中22例有子宫内膜增生,其中18例子宫内膜单纯增生,4例非典型增生;雄激素水平的高低与子宫内膜增生无关;胰岛素抵抗、肥胖和闭经≥3个月伴或不伴有月经淋漓不尽与子宫内膜增生密切相关;子宫内膜厚度≥7mm时可筛查出全部的子宫内膜增生患者。结论多囊卵巢综合征子宫内膜增生患者具有胰岛素抵抗、肥胖、闭经和月经淋漓不尽等特点,阴道超声检查可协助诊断子宫内膜增生。
Objective To investigate the clinical features of patients with polycystic ovary syndrome and endometrial hyperplasia. Methods A prospective study was conducted on 76 cases of PCOS patients with endometrial pathology, amenorrhea time, body mass index, serum glucose, insulin, sex hormone levels and vaginal ultrasound endometrial thickness measurement. Results In 76 cases, 22 cases had endometrial hyperplasia, of which 18 cases were endometrial hyperplasia and 4 cases were atypical hyperplasia; the level of androgen was not related to endometrial hyperplasia; insulin resistance, obesity and amenorrhea≥3 months Or not associated with menstrual dripping and endometrial hyperplasia closely related; endometrial thickness ≥ 7mm can be screened out all of the endometrial hyperplasia patients. Conclusions Patients with polycystic ovary syndrome endometrial hyperplasia have the characteristics of insulin resistance, obesity, amenorrhea and menstrual fluid dripping. Vaginal ultrasonography can help diagnose endometrial hyperplasia.