类风湿关节炎(RA)是一种常见的致残性疾病,发病2年即可出现不可逆的骨破坏。因缺少特异性诊断方法,常造成误诊和漏诊,导致关节畸形和功能丧失。目前国际上通用美国风湿病学会1987年诊断标准即主要依据临床表现、X线改变和类风湿因子(RF)检测。符合此标准时病人常已出现骨破坏,? Rheumatoid arthritis (RA) is a common disabling disease that occurs irreversibly after 2 years of onset. Due to the lack of specific diagnostic methods, often resulting in misdiagnosis and missed diagnosis, resulting in joint deformity and loss of function. Currently the international standard of diagnosis of the American College of Rheumatology in 1987 based mainly on clinical manifestations, X-ray changes and rheumatoid factor (RF) test. In line with this standard patients often have bone destruction ,?