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为探讨山莨菪碱血管活性作用可能的机理,在杂种犬离体血管制备进行丁一系列受体药理学方面的研究,结果表明: 1.在静息去内皮隐静脉血管环,较高浓度的乙酰胆碱(ACh,1)~(-6)～10~(-3)mol/L)引起血管平滑肌收缩(M_1-
In order to explore the possible mechanism of anisodamine vaso-vasospasm activity, a series of pharmacological studies were conducted in isolated vasculature of mongrel dogs. The results showed that: 1. Acetylcholine (ACh, 1) ~ (-6) -10 ~ (-3) mol / L) induced vascular smooth muscle contraction (M_1-