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IgA 肾病最初认为是一种预后良好的肾小球肾炎,晚近的观察发现,有10～30%患者在10～20年后发展为终末期肾衰(ESRF)。因此,有人认为 IgA 肾病并非为单一的疾病,可能存在预后良好和发展为ESRF 的二种不同的临床经过或疾病。本文旨在研究:①肾活检时高血压与其他参数之问的关系;②进行性高血压是本病进展的一个标志;③推测自出现高血压后的肾存活情况。病人和方法 209例 IgA 肾病,男性140例,女性69例。平均年龄30.6±10.9岁。患者均经肾活检确诊,并除外系统性疾病或肝脏疾病,平均随访6.3±4.0年,其中22例(男21例,女1例)进入 ESRF。
IgA nephropathy was originally considered to be a good prognosis of glomerulonephritis, recent observations found that 10 to 30% of patients 10 to 20 years after the development of end-stage renal failure (ESRF). Therefore, it is thought that IgA nephropathy is not a single disease, and there may be two different clinical pathologies or diseases that have a good prognosis and ESRF development. The purpose of this paper is to investigate: (1) the relationship between hypertension and other parameters during renal biopsy; (2) progressive hypertension is a hallmark of the disease; and (3) speculation of renal survival since hypertension. Patients and Methods 209 cases of IgA nephropathy, 140 males and 69 females. The average age was 30.6 ± 10.9 years. All patients were diagnosed with renal biopsy, except for systemic diseases or liver diseases. The patients were followed up for an average of 6.3 ± 4.0 years. Twenty-two of them (21 males and 1 females) entered ESRF.