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目的:通过观察活血化瘀法联合来氟米特片、美洛昔康分散片治疗对类风湿关节炎血液流变学的影响,探讨中西医结合治疗类风湿关节炎的优势。方法:对确诊的159例患者随机分为两组,对照组服用来氟米特片和美洛昔康分散片治疗,治疗组在此基础上加服自拟活血化瘀中药方剂治疗。两组均连续服用3个月为1个疗程,1个疗程后分别测定全血黏度、血浆黏度等指标,并进行疗效评定。结果:治疗后两组血液流变学指标均较治疗前降低(P<0.05),且治疗组改善更为明显(P<0.01),治疗组的血沉、全血黏度、血浆黏度改善与对照组比较P<0.01。结论:中西医结合治疗类风湿关节炎在改善微循环方面较单纯西医治疗更具有优势。
OBJECTIVE: To observe the effect of activating blood circulation and removing blood stasis combining with leflunomide tablets and meloxicam dispersible tablets on the hemorheology of rheumatoid arthritis, and to explore the advantages of combining traditional Chinese and western medicine in the treatment of rheumatoid arthritis. Methods: The 159 patients diagnosed were randomly divided into two groups. The control group was treated with leflunomide tablets and meloxicam dispersible tablets. On the basis of this, the treatment group was treated with Chinese medicine prescription of activating blood circulation and removing blood stasis. Two groups were taken for 3 months as a course of treatment, after a course of treatment were measured whole blood viscosity, plasma viscosity and other indicators, and efficacy evaluation. Results: After treatment, the indexes of hemorheology in both groups were lower than those before treatment (P <0.05), and the improvement in the treatment group was more obvious (P <0.01). The erythrocyte sedimentation rate, whole blood viscosity and plasma viscosity in the treatment group were significantly lower than those in the control group P <0.01 compared. Conclusion: The combination of traditional Chinese and western medicine treatment of rheumatoid arthritis in the improvement of microcirculation than Western medicine treatment more advantages.