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1 ACCORD研究[1]的背景在UKPDS研究后,证实在新诊断的2型糖尿病早期,经强化血糖控制后看到大致同DCCT研究的类似效果,看到糖尿病微血管并发症(眼、肾、神经等)的发生率显著降低,但大血管并发症经强化控制血糖后,心肌梗死也见下降但无统计学意义;为此后来的一些学者考虑是否血糖控制不到位,而致大血管并发症未见显著下降?ACCORD研究就在此背景下,企图从严控制血糖
1 Background of the ACCORD Study [1] After the UKPDS study, it was demonstrated that similar effects to DCCT studies were seen after intensive glycemic control in the newly diagnosed type 2 diabetes early stage and that diabetic microvascular complications (ocular, renal, neural Etc.), but the incidence of myocardial infarction was also decreased with no significant difference after intensive therapy of macrovascular complications; therefore, some scholars later considered whether the blood glucose control was not in place and caused no macrovascular complications See Significant Decline? ACCORD research is in this context, in an attempt to control blood sugar