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[目的]观察金霉素眼膏在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)手术创面中的应用效果.[方法]选择96例OSAHS患者,随机分为对照组(46例)和观察组(50例),两组均施行悬雍垂腭咽成形术(UPPP),观察组术中将金霉素眼膏涂布于手术创面后进行缝合,而对照组术中手术创面内未涂布任何药物后直接进行缝合,观察两组术后出血发生率、出血部位及程度、手术创面水肿程度、术后瘢痕形成程度及术后缝合线情况.[结果]观察组和对照组中术后出血率分别为6.5%和22.0%,相比较差异有统计学意义(P<0.05).观察组扁桃体下极出血2例,弥漫性出血1例;对照组扁桃体窝出血4例,扁桃体下极出血4例,弥漫性出血1例,其他出血2例.观察组Ⅰ度出血3例;对照组Ⅰ度出血3例,Ⅱ度出血5例,Ⅲ度出血3例.观察组手术创面水肿程度及瘢痕形成程度较对照组明显减轻(P<0.01).[结论]在OSAHS手术创面涂布给予金霉素眼膏后进行缝合的方法可有效减少术后出血,明显减轻出血及手术创面水肿程度,减轻手术创面术后瘢痕的形成.
[Objective] To observe the effect of chlortetracycline eye ointment on surgical wounds of obstructive sleep apnea-hypopnea syndrome (OSAHS). [Methods] Ninety-six patients with OSAHS were randomly divided into control group (46 cases) and observation group (50 cases). Uvulopalatopharyngoplasty (UPPP) was performed in both groups. In the observation group, chlortetracycline eye ointment was applied to the wounds after operation, while the control group was not coated with intraoperative wounds All the patients were directly sutured, and the incidence of postoperative bleeding, the location and extent of bleeding, the degree of wound edema, the degree of postoperative scar formation and postoperative suture were observed. [Results] The postoperative bleeding in observation group and control group (P <0.05) .There were 2 cases of tonsil hemorrhage and 1 case of diffuse hemorrhage in the observation group, 4 cases of tonsil hemorrhage and 4 cases of tonsil hemorrhage 4 in the control group 1 case of diffuse hemorrhage and 2 cases of other hemorrhage in the observation group, 3 cases of grade Ⅰ hemorrhage in observation group, 3 cases of grade Ⅰ hemorrhage in control group, 5 cases of grade Ⅱ hemorrhage and 3 cases of Ⅲ degree hemorrhage in observation group. (P <0.01). [Conclusion] In the OSAHS surgical wounds coated with gold The method of suturing after prime ointment can effectively reduce postoperative bleeding, bleeding and significantly reduce the degree of surgical wound edema, reduce scar formation in surgical wound.