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目的探讨喷昔洛韦乳膏联合卡介菌多糖核酸注射液治疗面部扁平疣患者的疗效。方法选取2012年8月至2013年9月医院门诊皮肤科收治的100例面部扁平疣患者资料,根据1:1配对方法将其分为对照组和观察组,各50例。对照组患者给予卡介菌多糖核酸注射液治疗,观察组患者在对照组基础上外涂喷昔洛韦乳膏,比较两组患者的治疗效果及不良反应发生情况。结果观察组患者治疗第1个疗程、第2个疗程总有效率均明显高于对照组,差异均有统计学意义(均P<0.05);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论采用喷昔洛韦乳膏联合卡介菌多糖核酸注射液治疗面部扁平疣患者,可明显提高临床疗效,安全可靠。
Objective To investigate the efficacy of penciclovir cream combined with BCG polysaccharide nucleic acid injection in the treatment of facial flat warts. Methods A total of 100 patients with facial flat warts admitted to the hospital outpatient department from August 2012 to September 2013 were selected and divided into control group and observation group according to 1: 1 matching method. Patients in the control group were treated with BCG polysaccharide nucleic acid injection. Patients in the observation group were treated with penciclovir cream on the basis of the control group. The therapeutic effect and adverse reactions of the two groups were compared. Results The total effective rate of the first course of treatment and the second course of treatment in the observation group was significantly higher than that of the control group (all P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The use of penciclovir cream combined with BCG polysaccharide nucleic acid injection in patients with facial flat warts can significantly improve the clinical efficacy, safe and reliable.