1977年Esterly等首次报告“发疹性毫毛囊肿”,共4例全为儿童,从4岁到9岁,呈持久性无症状的丘疹,分布于胸部,其中2例亦累及四肢。病理改变为真皮中部小囊肿,内含成层角化性物质和毫毛。作者最近遇见1例报告如下: 女性,18岁,病期6个月,无局部外伤史和家族史,皮疹分布于前胸剑突周围,有35～40个丘疹,呈不规则的散布。每个损害呈1～4毫米大小棕黑色、软的毛囊丘疹,表面光滑或结痂,少数受刺激的损害表面覆以痂皮,后者易除去。无同形反应现象,其它检查包括实验室检查均阴性。损害在10个月后自然消失,仅留下少数1～2毫米大的淡蓝色色素斑。未见复发。病理改变为真皮中部有小囊肿性结构,内含有 In 1977, Esterly et al. first reported “eruptive hairless cysts.” A total of 4 cases were children. From 4 to 9 years of age, they presented persistent asymptomatic pimples on the chest. Two of them also involved limbs. The pathological changes were small cysts in the middle of the dermis, which contained stratified keratinous material and hairs. The author recently met with 1 case report as follows: Female, 18 years old, 6 months old, no history of local trauma and family history, skin rash distributed around the chest xiphoid, 35 to 40 papules, irregularly spread. Each lesion was 1 to 4 mm in size brownish black, with soft follicular papules, smooth or crusted surfaces, and a few irritated lesions covered with scabs that were easily removed. There was no isomorphism and other tests including laboratory tests were negative. Damage naturally disappeared after 10 months, leaving only a few 1 to 2 mm large pale blue pigmented spots. No recurrences. The pathological change is a small cystic structure in the middle of the dermis.