韦格内肉芽肿是一种多系统性非特异性坏死性肉芽肿,较少见。其主要特点是侵犯上呼吸道及/或下呼吸道和肾脏。病因未明,可能与免疫有关。本文综合国内及作者报告尸检或病理活检证实共13例的临床、病理材料并结合文献加以讨论。病因及发病机理 Wegener’s granulomatosis is a multi-system non-specific necrotizing granuloma, rare. Its main feature is the violation of the upper respiratory tract and / or the lower respiratory tract and the kidneys. Etiology is unknown, may be related to immunity. In this paper, the domestic and author reports autopsy or biopsy confirmed a total of 13 cases of clinical and pathological materials and literature to be discussed. Etiology and pathogenesis