1986年1月,澳大利亚和美国在鼻内应用干扰素预防普通感冒的报道中,α-2干扰素的用量为5×10~6IU/天。某家庭首例患者发病后,其他家庭成员连续鼻内用药7天。结果发现,澳大利亚和美国组普通感冒发病率分别减少41%和39%。澳大利亚组用干扰素后,普通感冒病程缩短76%(6.3天至1.5天),但对所有其他呼吸道疾病病程仅缩短20% January 1986, Australia and the United States in the intranasal use of interferon in the prevention of the common cold in the report, the amount of interferon α-2 5 × 10 ~ 6IU / day. After the onset of the first patient in a family, other family members administered the drug continuously for 7 days. The results showed that the prevalence of common cold in Australia and the United States decreased by 41% and 39% respectively. In Australia, the duration of the common cold was shortened by 76% (6.3 days to 1.5 days) with interferon but only a 20% reduction in the duration of all other respiratory diseases