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一,与肾素有关的高血压发病机理血压是流动血液对血管壁的压力,而平均动脉压=心排出量×总周围血管阻力。所以心排出量和外周血管阻力是影响血压的最重要的直接因素,其他方面的因素间接影响血压．就这2个直接因素而言,高血压患者早期心排出量是增高的,到了晚期心排出量降到正常,而外周血管阻力的增加占优势。这种由高心排出量过渡到高外周血管阻力是一个很重要的过程。
First, the renin-related pathogenesis of hypertension Blood pressure is the pressure of blood flow on the vessel wall, and mean arterial pressure = cardiac output × total peripheral vascular resistance. Therefore, cardiac output and peripheral vascular resistance are the most important direct factors affecting blood pressure, and other factors indirectly affect blood pressure. In terms of these two direct factors, early cardiac output in hypertensive patients is increased, to late cardiac output dropped to normal, and peripheral vascular resistance increased predominance. This transition from high cardiac output to high peripheral vascular resistance is a very important process.