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目的观察对院前心跳呼吸骤停患者在心肺脑复苏过程中应用纳洛酮治疗的效果。方法将各种心跳呼吸骤停患者随机分为纳洛酮组及常规组。常规组立即给予胸外心脏按压、气管插管、电击除颤、静脉用药(肾上腺素、阿托品、利多卡因等)等基础心肺复苏术及高级生命支持。纳洛酮组除上述治疗措施外,同时给予盐酸纳洛酮2.0mg静脉注射,对比观察两组心肺脑复苏情况。结果纳洛酮组心肺复苏与脑复苏成功率均高于常规组,差异有统计学意义。结论纳洛酮能提高院前急救心肺脑复苏成功率。
Objective To observe the effect of naloxone treatment on cardiopulmonary resuscitation in patients with heartbeat and respiratory arrest before hospitalization. Methods A variety of cardiac arrest and respiratory arrest patients were randomly divided into naloxone group and conventional group. The routine group was given basic cardiopulmonary resuscitation and advanced life support such as chest compressions, endotracheal intubation, electric shock defibrillation, intravenous medication (epinephrine, atropine, lidocaine, etc.). Naloxone group in addition to the above treatment, while given naloxone hydrochloride 2.0mg intravenously, compared two groups of cardiopulmonary resuscitation. Results The success rate of cardiopulmonary resuscitation and cerebral resuscitation in naloxone group was higher than that in conventional group, the difference was statistically significant. Conclusion Naloxone can improve the success rate of cardiopulmonary resuscitation before hospital emergency.